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isavuconazonium sulfate will raise the stage or influence of ergotamine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.

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Contraindicated in labor and shipping and delivery owing to ergotamine’s oxytocic impact, and that is maximal in the third trimester

trofinetide will increase the amount or result of ergotamine by influencing hepatic/intestinal enzyme CYP3A4 metabolism.

procarbazine raises effects of caffeine by pharmacodynamic synergism. Contraindicated. Caffeine can create severe hypertensive crises or harmful cardiac arrhythmias if administered to patients taking a MAOI. All preparations made up of caffeine need to be made use of sparingly.

palbociclib will increase the degree or influence of ergotamine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Closely. The dose of delicate CYP3A substrates with a slim therapeutic index may perhaps have to be lessened if coadministered with palbociclib

Contraindicated (1)itraconazole will boost the level or result of ergotamine by impacting hepatic/intestinal enzyme CYP3A4 metabolism.

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ceritinib boosts levels of ergotamine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Prevent concurrent utilization of CYP3A substrates recognised to have slender therapeutic indices or substrates generally metabolized by CYP3A in the course of remedy with ceritinib; if use of such remedies is unavoidable, take more info into consideration dose reduction.